Difference Between Hodgkin and Non Hodgkin Lymphoma
Lymphoma is a cancer that affects the lymph system, a vital part of the immune system that helps protect the body against disease. There are two main types of lymphoma: Hodgkin lymphoma and non-Hodgkin lymphoma. Both are similar in many ways but have some key differences.
Hodgkin lymphoma
Hodgkin lymphoma is a type of lymphoma that arises from a specific type of abnormal B-cell called Reed-Sternberg cells. It usually begins in the lymph nodes in one part of the body and then spread to other parts. The main difference between Hodgkin and non-Hodgkin lymphoma is the presence of Reed-Sternberg cells, which occur in Hodgkin lymphoma but not in non-Hodgkin lymphoma.
Hodgkin lymphoma is typically diagnosed in young adults, and its symptoms include swollen lymph nodes, fatigue, fever, and weight loss. Treatment for Hodgkin lymphoma typically involves chemotherapy, radiation therapy, and stem cell transplantation.
Non-Hodgkin lymphoma
Non-Hodgkin lymphoma refers to a group of lymphomas that do not have Reed-Sternberg cells. It can develop from either B-cells or T-cells and usually affects many lymph nodes throughout the body. Non-Hodgkin lymphoma is more common than Hodgkin lymphoma, and there are many different subtypes. The most common symptoms of non-Hodgkin lymphoma include swollen lymph nodes, fever, night sweats, and weight loss.
Diagnostic tests for non-Hodgkin lymphoma can include blood tests, lymph node biopsies, bone marrow biopsies, and imaging tests, such as CT or PET scans. Treatment for non-Hodgkin lymphoma will depend on the type and severity of the disease but may include chemotherapy, radiation therapy, immunotherapy, or stem cell transplantation.
Conclusion
Lymphoma is a complex disease that can present in different ways. Hodgkin and non-Hodgkin lymphoma have some similarities, but they are also distinct types of cancer. If you or someone you know is experiencing symptoms that could be related to lymphoma, it is important to see a doctor for a professional diagnosis and treatment plan.
Table difference between hodgkin and non hodgkin lymphoma
| Category | Hodgkin Lymphoma | Non-Hodgkin Lymphoma |
|---|---|---|
| Definition | A cancer of the lymphatic system, characterized by the presence of Reed-Sternberg cells. | A cancer of the lymphatic system that does not involve Reed-Sternberg cells. |
| Age | Most commonly affects people in their late 20s to early 30s and those over 60 years old. | Can occur at any age, but is more common in people over 60 years old. |
| Symptoms | Enlargement of one or more lymph nodes, unexplained weight loss, night sweats, fever, and itching. | Enlargement of one or more lymph nodes, unexplained weight loss, night sweats, fever, and itching. |
| Treatment | Chemotherapy, radiation therapy, stem cell transplant, and/or immunotherapy. | Chemotherapy, radiation therapy, stem cell transplant, and/or immunotherapy. |
| Prognosis | Overall good prognosis with high remission rates, even in advanced stages. | Prognosis varies depending on the type and stage of the lymphoma. Some types have a good prognosis while others have a poorer prognosis and lower remission rates. |